Human Sera
Cayman Chemical RauwolscInhydrochlorIde 100mg
A butaprost analog with a 56-double bond and without the methyl ester
Cayman Chemical FInasterIde 100mg
An L-type calcium channel blocker reduces amplitude of spontaneous contractions in isolated rabbit ileum at 1 M reduces TGF-b-induced calcium oscillations in human fibroblasts at 1 M prevents impairment of lung function in a mouse model of bleomycin-induced pulmonary fibrosis at 10 mg/kg per day reduces increases in mean arterial blood pressure induced by angiotensin II in spontaneously hypertensive rats at 10 g/kg
Cayman Chemical TomatIdInhydrochlorIde 100mg
A mixture of AMP derivatives has been used to study AMP-dependent cellular processes
Cayman Chemical Fenoldopamesylate 100mg
A mixture of asialo ganglioside GM1 with C181 and C201 sphingoid backbones a component of cellular lipid rafts a glycolipid receptor for P. aeruginosa flagellin ligation stimulates defensive reponses in host cells including extracellular ATP release calcium mobilization and ERK1/2 phosphorylation the percentage of asialo ganglioside GM1-positive NK and CD8 T cells in lung is increased in a mouse model of RSV infection compared with healthy animals depletion of asialo ganglioside GM1-positive NK and T cells reduces IFN-Y levels in the lung reduces weight loss and increases lung viral load in RSV-infected mice
Cayman Chemical FormontIn 100mg
A nucleoside analog with diverse biological activities is converted to cordycepin triphosphate which inhibits ATP-dependent DNA and RNA synthesis incorporates into DNA and RNA in SK-HEP-1 cells is active against B. subtilis at 0.1-1 mg/ml increases IL-10 secretion and mRNA expression in isolated human PBMCs at 24 Ug/ml increases survival of mice infected with C. albicans or C. krusei at 1 mg/kg per day
Cayman Chemical NundecnoylLHomoserIn lac 50mg
A cell-permeable analog of pifithrin-a that blocks p53-mediated expression of p21/WAF1 and apoptosis in cortical neurons ten-fold more potently than pifithrin-a suppresses p53-mediated TGF-B1 expression in human proximal tubular cells and attenuates steatosis and liver injury in mice fed a high-fat diet
Cayman Chemical LasofoxIfentartrate 50mg
A DNA alkylating agent inhibits cell growth and induces cell cycle arrest at the G2/M phase in C6 cells at 10 UM reduces tumor growth in a C6 rat glioma model at 0.3 and 6.7 mg/kg reduces the number of amyloid-B plaques and brain levels of AB40 as well as increases brain levels of sAPP in the APP/PS1 transgenic mouse model of Alzheimers disease at 0.5 mg/kg i.p.
Cayman Chemical CytIdIn 5trIphosphATsod 100mg
A highly sensitive rhodamine phenylglyoxal-based fluorophore that specifically detects protein citrullination via a chemoselective reaction between glyoxal and citrulline reacts with any citrulline-containing protein and can be analyzed with fluorescent imaging (Ex. 532 nm Em. 580 nm) limit of detection of ~10 ng for citrullinated histone H3 and ~1 ng for autodeiminated PAD4 when applied at 100 UM for 30 minutes at acidic pH
Cayman Chemical DetomIdInhydrochlorIde 100mg
An odoriferous component of musk that has been shown to exhibit anti-inflammatory effects by reducing the expression of proinflammatory cytokines both in vitro and in vivo also reported to be both cardioprotective and neuroprotective during conditions of ischemia and to promote proliferation and differentiation of neural stem cells
Cayman Chemical BetaxololhydrochlorIde 50mg
Immunogen Purified ovine COX-1 Host Mouse Species Reactivity ( ) Human mouse rat bovine (-) Other species not tested Cross Reactivity ( ) Human ovine COX-2 (-) Mouse COX-2 Applications IHC WB
Cayman Chemical 15 S-Latnoprost 50mg
A specific cell-permeable inhibitor of S6K1 (IC50 160 nM) does not inhibit S6K2 MSK or RSK or many other unrelated kinases under conditions in which it inhibits S6K1 activity
Cayman Chemical 4CLOro3 5dImethylphenoxy 50mg
An expected metabolite produced during metabolism of AB-CHMINACA in the liver intended for forensic and research applications
Cayman Chemical MIdodrInhydrochlorIde 100mg
A zwitterionic long-chain acylcarnitine used to improve in vivo absorption of certain hydrophilic compounds especially through mucosal membranes
Cayman Chemical EmpaglIflozIn 100mg
An inhibitor of FAAH MAGL and ABHD6 inhibits in vitro hFAAH mFAAH hMAGL mMAGL and mABHD6 (IC50s 1.9 3.2 1400 410 and 850 nM respectively) inhibits in vivo mFAAH (≥1.25 mg/kg) mMAGL (12.5 mg/kg) and mABHD6 (12.5 mg/kg) alleviates morphine withdrawal in mice